YBX1 antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB, IHC, IP, IF
  • 特异性:Human, Mouse; other species not tested.

产品详情

  • 产品名称
    YBX1 antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    YBX1 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in MCF7 cells, HEK-293 cells, HeLa cells, Jurkat cells, mouse spleen tissue. Positive IHC detected in human placenta tissue, human cervical cancer tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 50 kDa
  • 抗体应用
    ELISA, WB, IHC, IP, IF
  • 应用推荐

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

    IHC: 1:20-1:200

    IF: 1:20-1:200

  • 特异性
    Human, Mouse; other species not tested.
  • 蛋白别名
    BP 8, CBF A, CSDA2, CSDB, DBPB, DNA binding protein B, EFI A, Enhancer factor I subunit A, MDR NF1, NSEP 1, NSEP1, Y box binding protein 1, Y box transcription factor, YB 1, YB1, YBX1
  • 制备方法
    This antibody was obtained by immunization of YBX1 recombinant protein (Accession Number: NM_004559). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    Y box binding protein 1(YBX1) is one of cis-acting elements which has a role in regulation of the expression of HLA class II genes. YBX1 is great of importance in regulation of PTP1B expression. It can bind to splice sites mediate pre-mRNA alternative splicing regulation. Also it involves in the regulation of translation by modulation of the interaction between the mRNA and eukaryotic initiation factors. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation

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