Active against G+ bacteria S. aureus ATCC 6535, S. saprophyticus, B. subtilis CCT 2471 (MIC 15-30 ug/ml), and G- bacteria E. coli CCT 1371, E. cloacae ACCT 23355, K. pneumoniae ACCT 13883, P. aeruginsa ACCT 27853 (MIC 15 ug/ml), and yeast C. albicans (MIC 2.5 ug/ml). Jelleines are produced constitutively by the workers and secreted into Royal Jelly. Compared to jellein-I, jellein-II only contains one additional residue T at the N-terminus. Jelleine-II has Antibacterial, Antifungal activity. Jelleine-II was found in honeybees, Apis mellifera.
Fontana R, Mendes MA, de Souza BM, Konno K, César LM, Malaspina O, Palma MS. Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera). Peptides. 2004 Jun;25(6):919-28.