Anti-MSR1/CD204 antibody

多克隆

兔

兔IgG

Rabbit polyclonal to MSR1/CD204

ELISA, WB

Human MSR1 / CD204

MSR, Scvr, MRS-A, MSR-A, SR-AI, SR-AII, Scara1, SRA, SR-A, CD204, phSR1, phSR2, SCARA1, CD204, MRS-A, MSR, MSR1, Msr1, MSR-A, phSR1, phSR2, Scara1, SCARA1, Scvr, SR-A, SR-AI, SR-AII

Produced in rabbits immunized with purified, recombinant Human MSR1 / CD204 (rh MSR1 / CD204; NP_619729.1; Lys77-Leu451). MSR1 / CD204 specific IgG was purified by Human MSR1 / CD204 affinity chromatography.

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1 and SCARA1, is a single-pass type I I membrane protein which contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer.

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