- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP, IF
- 特异性:Human; other species not tested.
产品详情
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产品名称
XPG antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
XPG Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive WB detected in HeLa cells, Jurkat cells, K-562 cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 200 kDa
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抗体应用
ELISA, WB, IP, IF
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IF: 1:20-1:200
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特异性
Human; other species not tested.
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蛋白别名
COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC
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制备方法
This antibody was obtained by immunization of XPG recombinant protein (Accession Number: NM_000123). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].