重组小鼠TFRC蛋白

小鼠

人胚胎肾细胞（HEK293）

Cys 89 - Phe 763

A DNA sequence encoding the extracellular domain of mouse TFRC (Q62351) (Cys 89-Phe 763) was fused with a polyhistidine tag at the N-terminus.

> 92 % as determined by SDS-PAGE

The recombinant mouse TFRC comprises 694 amino acids and predicts a molecular mass of 78.3 kDa. The apparent molecular mass of mouse TFRC is approximately 80 kDa in SDS-PAGE under reducing conditions.

TFR1; 2610028K12RIK; T9; AI195355; TFRC; TR; TRFR; MTVR1; AI426448; E430033M20RIK; MTVR-1; CD71; P90; AU015758; TRANSFERRIN RECEPTOR; TFR

Transferrin receptor protein 1

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity).

Lyophilized from sterile PBS, pH 7.4
1. 5 % trehalose and mannitol are added as protectants before lyophilization.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg of the protein as determined by the LAL method

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.