Recombinant Human Transmembrane protein 204 (TMEM204) Fragment (aa 27-103) - A high-quality, soluble protein fragment ideal for studying cell-cell adhesion mechanisms and paracellular permeability regulation. This 77-amino acid fragment represents a stable, structurally optimized region of the Claudin-like protein 24, specifically designed for structural biology and biochemical applications.

Transmembrane protein 204 (TMEM204), also known as Claudin-like protein 24, is a multi-pass membrane protein that plays a crucial role in regulating paracellular permeability and participates in cell-cell interactions through adherens junctions. The protein localizes to cell junctions and the cell membrane, where it colocalizes with beta-catenin in adherens complexes. This strategic positioning enables TMEM204 to contribute to intercellular communication and barrier function maintenance. The full-length protein's involvement in these fundamental cellular processes makes it an important target for research in epit