- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB
- 特异性:Human; other species not tested.
产品详情
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产品名称
TLE1 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG2b
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抗体描述
TLE1 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 85-95 kDa
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抗体应用
ELISA, WB
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
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特异性
Human; other species not tested.
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蛋白别名
E(Sp1) homolog, ESG, ESG1, GRG1, TLE1
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制备方法
This antibody was obtained by immunization of TLE1 recombinant protein (Accession Number: NM_005077). Purification method: Protein A purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Transducin-like enhancer protein 1(TLE1) is a transcriptional corepressor. It can bind to and regress expression of many transcription factors such as NFkB, which is mediated by FOXA2, CTNNB1 and TCF family member in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Expression of TLE1 is highest in skeletal muscle and liver, moderate in placenta, heart, kidney, and spleen, and weak in all other tissues including brain.