Introducing the recombinant human Retinoic acid receptor RXR-beta (RXRβ) fragment (residues 203-533), a high-purity protein designed to encompass the NR LBD domain. This fragment serves as an essential tool for investigating retinoic acid signaling, ligand binding, and gene regulation mechanisms in nuclear receptor research.

Retinoic acid receptor RXR-beta (RXRβ), encoded by the RXRB gene, functions as a receptor for retinoic acid, binding as heterodimers to retinoic acid response elements (RARE) in response to ligands such as all-trans or 9-cis retinoic acid. It plays a critical role in regulating gene expression across diverse biological processes. The protein is localized primarily in the nucleus, with additional presence observed in the cytoplasm, highlighting its dynamic involvement in cellular signaling pathways.