This product is a recombinant fragment (residues 31-310) of the human Ribosomal L1 domain-containing protein 1 (RSL1D1), also known as CATX-11 or PBK1. The fragment has been carefully selected for stability and solubility, making it an ideal tool for investigating the protein's roles in cellular senescence, apoptosis, and DNA damage response.

The full-length RSL1D1 protein is a key regulator of cellular senescence, primarily through its inhibition of PTEN translation. It also functions as a pro-apoptotic regulator in response to DNA damage. RSL1D1 is localized in the nucleus and nucleolus, where it colocalizes with ING1 following UV stress, highlighting its involvement in stress response pathways. These functions underscore its significance in cellular aging, apoptosis, and DNA damage mechanisms, making it a valuable target for research in cancer biology and aging studies.