- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IF, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
RCN2 antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
RCN2 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue, human testis tissue. Positive IF detected in HepG2 cells. Positive WB detected in human brain tissue, HEK-293 cells, mouse lung tissue. Positive IP detected in mouse lung tissue. Observed molecular weight by Western-blot: 55 kDa
-
抗体应用
ELISA, WB, IHC, IF, IP
-
应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
IF: 1:20-1:200
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
Calcium binding protein ERC 55, E6 binding protein, E6BP, ERC 55, ERC55, RCN2, ReticulOCalbin 2, TCBP49
-
制备方法
This antibody was obtained by immunization of RCN2 recombinant protein (Accession Number: NM_002902). Purification method: Antigen affinity purified.
-
组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
Reticulocalbin 2 (RCN2) is a Ca(2+)-binding protein that is specifically localized in the endoplasmic reticulum (ER). It is also termed ERC-55, i.e. ER calcium-binding protein of 55 kDa. It is a single copy gene and is encoded by an approximately 1900-base mRNA, which shows a ubiquitous expression pattern. The protein comprises an amino-terminal signal sequence followed by six copies of the EF-hand Ca2+ binding motif.
-
参考文献
- Li L, Sun L, Gao F. Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proceedings of the National Academy of Sciences of the United States of America. 107(4):1402-7. 2010.
- Manichaikul A, Wang Q, Shi YL, Zhang Z, Leitinger N, Shi W. Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression. American journal of physiology. Heart and circulatory physiology. 301(3):H1056-61. 2011.
- Yokoi N, Fukata Y, Kase D. Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nature medicine. 21(1):19-26. 2015.