产品详情
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产品名称
重组人RAD52蛋白
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蛋白种属
人
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表达宿主
大肠杆菌
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蛋白序列
MSKIKHHHHHHGGSMSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRP
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克隆构建
DNA encoding 1-210 aa (P43351) were fused with N-terminal 6His tag.
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蛋白纯度
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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蛋白活性
Not tested.
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分子量
Predictes a molecular mass of 24.75 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 25 kDa band.
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蛋白全名
DNA repair protein RAD52 homolog
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蛋白描述
Recombinant Human DNA repair protein RAD52 homolog (fragment 1-210) is a high-quality protein fragment designed for structural and biochemical studies. This 210-amino acid fragment was computationally selected for stability and solubility, offering researchers a reliable tool to investigate RAD52's central role in DNA repair and genetic recombination.
The full-length DNA repair protein RAD52 homolog plays a critical role in maintaining genomic integrity through double-stranded break repair. Located in the nucleus, this protein facilitates genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and stimulating the RAD51 recombinase activity. These functions make RAD52 essential for understanding DNA damage response mechanisms and developing potential therapeutic strategies for conditions involving DNA repair deficiencies.
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发货形式
Lyophilized from sterile PBS, pH 7.4
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内毒素
Not tested.
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保存条件
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.