- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
PYCR1 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
PYCR1 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, human brain tissue. Positive IP detected in Raji cells. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 34 kDa
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抗体应用
ELISA, WB, IHC, IP
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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特异性
Human, Mouse; other species not tested.
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蛋白别名
P5C, P5C reductase 1, P5CR, P5CR 1, PIG45, PP222, PYCR, PYCR1
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制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_006907). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
PYCR1,also named as P5CR1, belongs to the pyrroline-5-carboxylate reductase family. It is a housekeeping enzyme that catalyzes the last step in proline biosynthesis. PYCR1 can utilize both NAD and NADP, but has higher affinity for NAD. It is involved in the cellular response to oxidative stress. Mutation in PYCR1 will cause ARCL type II(ARCL2B ). Some mutation will cause DeBarsy syndrome (DBS) which is characterized by progeroid features, ophthalmological abnormalities, intrauterine growth retardation, and cutis laxa. The MW of PYCR1 is about 33-35kd.