- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, IP, WB
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
PPP3R1 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
PPP3R1 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue. Positive WB detected in K-562 cells, HeLa cells, human stomach tissue. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 19 kDa
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抗体应用
ELISA, IHC, IP, WB
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应用推荐
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
Calcineurin subunit B type 1, CALNB1, CNA2, CNB, CNB1, PPP3R1
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制备方法
This antibody was obtained by immunization of PPP3R1 recombinant protein (Accession Number: NM_000945). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.
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参考文献
- Su Z, Xin S, Xu L. The calcineurin B subunit induces TNF-related apoptosis-inducing ligand (TRAIL) expression via CD11b-NF-κB pathway in RAW264.7 macrophages. Biochemical and biophysical research communications. 417(2):777-83. 2012.