- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB
- 特异性:Mouse, Rat
产品详情
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产品名称
PDE8A Polyclonal Antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Polyclonal antibody to PDE8A
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抗体应用
WB
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应用推荐
WB 1:500 - 1:2000
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特异性
Mouse, Rat
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蛋白别名
PDE8A, HsT19550, phosphodiesterase 8A
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制备方法
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1).
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组分
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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储存方法
Store at -20℃. Avoid freeze / thaw cycles.
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背景介绍
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine.