- 抗体类型:单克隆
- 抗体来源:小鼠
- 抗体应用:ELISA, WB, IF, IHC
- 特异性:Human; other species not tested.
产品详情
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产品名称
ORM1/2 antibody
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抗体类型
单克隆
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抗体来源
小鼠
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抗体亚型
小鼠IgG1
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抗体描述
ORM1/2 Mouse Monoclonal antibody. Positive IHC detected in human liver tissue, human liver cancer tissue. Positive IF detected in HepG2 cells. Positive WB detected in Human Blood. Observed molecular weight by Western-blot: 41kDa
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抗体应用
ELISA, WB, IF, IHC
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应用推荐
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:10-1:100
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特异性
Human; other species not tested.
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蛋白别名
AGP 1, AGP A, AGP1, Alpha 1 acid glycoprotein 1, OMD 1, ORM, ORM1, orosomucoid 1
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制备方法
This antibody was obtained by immunization of ORM1/2 recombinant protein (Accession Number: NM_000607). Purification method: Protein G purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (ORM1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in human plasma which may be due to the glycosylation of ORM1 or the dimer formation of the protein. This anibody recognizes both ORM1 and ORM2.