重组小鼠Ddr2蛋白

小鼠

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Mouse Ddr2/Ntrkr3/Tkt/Tyro10 Gln24-Arg399 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

Ntrkr3; Tkt; Tyro10

discoidin domain receptor family, member 2(Ddr2)

Discoidin domain receptor-2 (DDR2) is a cell surface tyrosine kinase receptor that can be activated by soluble collagen and has been implicated in diverse physiological functions including organism growth and wound repair. DDR2 binds to and is activated by collagen I, II, III, V, and X, with the notable exception of basement membrane collagen IV. DDR2 is expressed in connective tissues arising from embryonic mesoderm. DDR2 regulates cell proliferation, cell adhesion, migration, and extracellular matrix remodeling.

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.