重组人MARHB蛋白

产品详情

  • 产品名称
    重组人MARHB蛋白
  • 蛋白种属
    人
  • 表达宿主
    大肠杆菌
  • Unitprot ID
  • 蛋白序列
    MNHKVHHHHHHGGSHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLVEKVQ
  • 克隆构建
    DNA encoding 166-244 aa (A6NNE9) were fused with N-terminal 6His tag.
  • 蛋白纯度
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • 蛋白活性
    Not tested.
  • 分子量
    Predictes a molecular mass of 10.85 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 11 kDa band.
  • 蛋白全名
    E3 ubiquitin-protein ligase MARCHF11
  • 蛋白描述

    Recombinant protein fragment of human E3 ubiquitin-protein ligase MARCHF11 (residues 166-244), a stable and soluble unit ideal for structural and biochemical studies of ubiquitin-mediated protein regulation.

    E3 ubiquitin-protein ligase MARCHF11 (EC 2.3.2.27) is a membrane-associated RING finger protein that functions as an E3 ubiquitin ligase, accepting ubiquitin from E2 conjugating enzymes and directly transferring it to substrates such as CD4. It plays a role in ubiquitin-dependent protein sorting during spermatid development and is localized to cytoplasmic vesicle membranes as a multi-pass membrane protein. This fragment represents a computationally selected region optimized for experimental analysis of its functional domains.

  • 发货形式
    Lyophilized from sterile PBS, pH 7.4
  • 内毒素
    Not tested.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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