Recombinant Human LRFN2 (Leucine-rich repeat and fibronectin type-III domain-containing protein 2) fragment (residues 21-379) is a high-purity protein designed for neuroscience and cell biology research. This fragment fully encompasses the LRRNT, LRRCT, and Ig-like functional domains, making it an ideal tool for studying neurite outgrowth, NMDA receptor regulation, and synaptic adhesion mechanisms.

Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (LRFN2), also known as Synaptic adhesion-like molecule 1, is a membrane protein that promotes neurite outgrowth in hippocampal neurons and enhances cell surface expression of NMDA receptor subunits GRIN1 and GRIN2A. It is localized to the postsynaptic cell membrane and synapses, where it may play a role in redistributing DLG4 to the cell periphery. As a single-pass type I membrane protein, LRFN2 functions in synaptic adhesion and neuronal development, making it a significant target for neurobiological research.