- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IP, IF
- 特异性:Human,Mouse,Rat; other species not tested.
LMP2 antibody
产品详情
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产品名称
LMP2 antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
LMP2 Rabbit Polyclonal antibody. Positive IP detected in Raji cells. Positive WB detected in Raji cells, HepG2 cells, rat spleen tissue. Positive IF detected in HepG2 cells. Positive IHC detected in human lymphoma tissue, human tonsillitis tissue. Observed molecular weight by Western-blot: 21-23 kDa
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抗体应用
ELISA, WB, IHC, IP, IF
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
IF: 1:50-1:500
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
20S proteasome, beta1i, LMP2, Low molecular mass protein 2, Macropain chain 7, Proteasome chain 7, Proteasome subunit beta 1i, Proteasome subunit beta type 9, PSMB6i, PSMB9, RING12
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制备方法
This antibody was obtained by immunization of LMP2 recombinant protein (Accession Number: NM_002800). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
PSMB9, also named as LMP2, PSMB6i and RING12, belongs to the peptidase T1B family. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. High expression of PSMB9 associated with the poor prognosis of patients with NPC.
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参考文献
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