LATS1 antibody

0 条评论 | 添加你的评论
  • 抗体类型:多克隆
  • 抗体来源:兔
  • 抗体应用:ELISA, WB, IHC
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    LATS1 antibody
  • 抗体类型
    多克隆
  • 抗体来源
    兔
  • 抗体亚型
    兔IgG
  • 抗体描述
    LATS1 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, K-562 cells, mouse cerebellum tissue, SH-SY5Y cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 140kd,120kd
  • 抗体应用
    ELISA, WB, IHC
  • 应用推荐

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    h warts, LATS1, WARTS, WARTS protein kinase, wts
  • 制备方法
    This antibody was obtained by immunization of LATS1 recombinant protein (Accession Number: BC015665). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    LATS1(Large tumor suppressor homolog 1) is also named as WARTS and belongds to the AGC Ser/Thr protein kinase family. The gene encodes a highly conserved (from fly to human) protein kinase that plays a crucial role in the prevention of tumor formation by controlling the progression of mitosis. The expression of both long(170 kDa) and short lats1 isoforms(120 kDa) in vertebrate retinal cells raises the possibility that these lats1 proteins may act as negative key regulators of the cell cycle each of them performing a unique role.(PMID:15777619). In mammalian cells, LATS1 was phosphorylated in a cell cycle-dependent manner and complexed with CDC2 in early mitosis(PMID:9988268).
  • 参考文献
    • <

抗体定制服务: 纽普生物（NovoPro）提供单克隆抗体及多克隆抗体定制服务

声明：本公司出售产品只能用于科研目的，不得用于诊断或者治疗！