- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IF
- 特异性:human; other species not tested.
产品详情
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产品名称
KISS1R-Specific antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
KISS1R-Specific Rabbit Polyclonal antibody. Positive IF detected in MCF-7. Positive WB detected in SH-SY5Y cells, MCF7 cells. Observed molecular weight by Western-blot: 43-45kd,75kd
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抗体应用
ELISA, WB, IF
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:10-1:100
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特异性
human; other species not tested.
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蛋白别名
KISS1R, KISS1 receptor, HOT7T175, Hypogonadotropin 1, AXOR12
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制备方法
This antibody was obtained by immunization of Peptide (Accession Number: NM_032551). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
receptor for metastin (kisspeptin-54, 13, 14, 10), C- terminally amidated peptides of KiSS-1. KiSS-1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some other carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.