- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
KDM5C antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
KDM5C Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 171-180 kDa
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抗体应用
ELISA, WB, IF
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应用推荐
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:50-1:500
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
DXS1272E, Histone demethylase JARID1C, JARID1C, KDM5C, lysine (K) demethylase 5C, Lysine specific demethylase 5C, MRXJ, MRXSJ, Protein SmcX, Protein Xe169, SMCX, XE169
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制备方法
This antibody was obtained by immunization of KDM5C recombinant protein (Accession Number: NM_001282622). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
KDM5C belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell growth and differentiation [PMID:21575681]KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues [PMID:17320160,17320161].