- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, WB, IP
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
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产品名称
IVD antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
IVD Rabbit Polyclonal antibody. Positive IP detected in MCF-7 cells. Positive WB detected in MCF-7 cells, human brain tissue, Transfected HEK-293 cells. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 41 kDa
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抗体应用
ELISA, IHC, WB, IP
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应用推荐
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:20-1:200
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特异性
Human,Mouse,Rat; other species not tested.
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蛋白别名
ACAD2, IVD
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制备方法
This antibody was obtained by immunization of IVD recombinant protein (Accession Number: NM_002225). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
IVD(Isovaleryl CoA dehydrogenase, mitochondrial) is a member of the acylCoA dehydrogenase family and is involved in the catabolism of leucine. In size, IVD precursor and mature proteins produced by class I mutants are indistinguishable from their normal counterparts. Class II, III, and IV mutants make IVD precursor proteins 42 kD in size rather than the normal 45 kD(PMID:2063866). It has 2 isoforms produced by alternative splicing.
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参考文献
- Ryu MJ, Lee C, Kim J, Shin HS, Yu MH. Proteomic analysis of stargazer mutant mouse neuronal proteins involved in absence seizure. Journal of neurochemistry. 104(5):1260-70. 2008.
- Gu L, Jones AD, Last RL. Broad connections in the Arabidopsis seed metabolic network revealed by metabolite profiling of an amino acid catabolism mutant. The Plant journal : for cell and molecular biology. 61(4):579-90. 2010.
- Horn S, Kirkegaard JS, Hoelper S. Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo. Molecular endocrinology (Baltimore, Md.). 30(1):133-43. 2016.