重组小鼠IGFBP4蛋白

产品详情

  • 产品名称
    重组小鼠IGFBP4蛋白
  • 蛋白种属
    小鼠
  • 表达宿主
    人胚胎肾细胞（HEK293）
  • Unitprot ID
    P47879
  • 蛋白序列
    Met 1 - Glu 254
  • 克隆构建
    A DNA sequence encoding the extracellular domain (Met 1-Glu 254) of mouse IGFBP4 (NP_034647.1) precursor was expressed with a C-terminal polyhistidine tag.
  • 蛋白纯度
    > 95 % as determined by SDS-PAGE
  • 蛋白活性
    Measured in a serumfree cell proliferation assay using MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. 1988, Cancer Research 48: 4083.). The ED50 for this effect is typically 0.1-0.6 μg/ml.
  • 分子量
    The secreted recombinant mouse IGFBP4 consists of 244 amino acids and has a calculated molecular mass of 27.2 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 38 kDa protein in SDS-PAGE under reducing conditions.
  • 蛋白别名
    BP-4; DEB2; HT29-IGFBP; IBP4; IGFBP-4; AI875747; IGFBP4; RP23-333D2.6
  • 蛋白全名
    Insulin-like growth factor-binding protein 4
  • 蛋白描述
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 发货形式
    Lyophilized from sterile PBS, pH 7.4
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    < 1.0 EU per μg of the protein as determined by the LAL method
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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