Recombinant Human Immunoglobulin Kappa Constant (IGKC) Fragment (1-107) – a high-purity protein encompassing the complete Ig-like domain, ideal for investigating antibody structure, B-cell receptor signaling, and humoral immune responses in research applications.

The Immunoglobulin Kappa Constant (IGKC) protein represents the constant region of immunoglobulin light chains, which are critical components of antibodies produced by B lymphocytes. In humoral immunity, membrane-bound immunoglobulins act as antigen receptors on B cells, triggering clonal expansion and differentiation into antibody-secreting plasma cells upon antigen binding. Secreted immunoglobulins then mediate effector functions to eliminate antigens. Each antibody's antigen-binding site is formed by variable domains of heavy and light chains, with the constant region (such as IGKC) contributing to antibody stability and function. The full-length protein is localized to the cell membrane or secreted into the extracellular space, playing a