重组人SERPINB12蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human SERPINB12 Met1-Pro425 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

serpin family B member 12(SERPINB12)

Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.

Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.