重组人ADH7蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human ADH7 Met1-Phe386 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide(ADH7)

Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.

Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.