- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IP, IF, FC, IHC
- 特异性:Human, Mouse, Rat; other species not tested.
产品详情
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产品名称
GRP78/BIP antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
GRP78/BIP Rabbit Polyclonal antibody. Positive FC detected in HeLa cells. Positive IHC detected in human pancreas cancer tissue, human brain tissue, human breast cancer tissue, human colon cancer tissue, mouse heart tissue. Positive IF detected in HepG2 cells. Positive IP detected in MCF-7 cells. Positive WB detected in HepG2 cells, BxPC-3 cells, HeLa cells, MCF7 cells, rat liver tissue, TN treated Hela cells. Observed molecular weight by Western-blot: 78 kDa
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抗体应用
ELISA, WB, IP, IF, FC, IHC
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100
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特异性
Human, Mouse, Rat; other species not tested.
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蛋白别名
BIP, GRP 78, GRP78, HSP A5, HSPA5, MIF2
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制备方法
This antibody was obtained by immunization of GRP78/BIP recombinant protein (Accession Number: NM_005347). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.
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参考文献
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