FAK antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, IHC, IP, WB, IF
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    FAK antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    FAK Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in MCF7 cells, A431 cells, HEK-293 cells, HeLa cells, Jurkat cells, NIH/3T3 cells. Positive IHC detected in human gliomas tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 110 kDa
  • 抗体应用
    ELISA, IHC, IP, WB, IF
  • 应用推荐

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:1000-1:10000

    IHC: 1:20-1:200

    IF: 1:20-1:200

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    FADK, FADK 1, FAK, FAK1, FOCal adhesion kinase 1, pp125FAK, Protein tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2
  • 制备方法
    This antibody was obtained by immunization of FAK recombinant protein (Accession Number: BC028733). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals (PMID:19664602). It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage (PMID:20966971). This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
  • 参考文献
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