- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, IHC, IP, WB, IF
- 特异性:Human,Mouse,Rat; other species not tested.
产品详情
-
产品名称
FAK antibody
-
抗体类型
多克隆
-
抗体来源
兔
-
抗体亚型
兔IgG
-
抗体描述
FAK Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in MCF7 cells, A431 cells, HEK-293 cells, HeLa cells, Jurkat cells, NIH/3T3 cells. Positive IHC detected in human gliomas tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 110 kDa
-
抗体应用
ELISA, IHC, IP, WB, IF
-
应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:20-1:200
-
特异性
Human,Mouse,Rat; other species not tested.
-
蛋白别名
FADK, FADK 1, FAK, FAK1, FOCal adhesion kinase 1, pp125FAK, Protein tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2
-
制备方法
This antibody was obtained by immunization of FAK recombinant protein (Accession Number: BC028733). Purification method: Antigen affinity purified.
-
组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
储存方法
Store at -20℃. DO NOT ALIQUOT
-
背景介绍
FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals (PMID:19664602). It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage (PMID:20966971). This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
-
参考文献
- <