EEF1E1 antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, IHC, WB
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    EEF1E1 antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    EEF1E1 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in HepG2 cells, HEK-293 cells, human testis tissue, Jurkat cells, SKOV-3 cells. Observed molecular weight by Western-blot: 20kd
  • 抗体应用
    ELISA, IHC, WB
  • 应用推荐

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    AIMP3, EEF1E1, Elongation factor p18, P18
  • 制备方法
    This antibody was obtained by immunization of EEF1E1 recombinant protein (Accession Number: NM_004280). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    During the translation processes, aminoacyl-tRNA synthetases (ARSs) ligate specific amino acids to tRNAs. Together with non-enzymatic proteins called ARS-interacting multifunctional proteins (AIMPs), the ARSs form a macromolecular complex [PMID:15286174]. This complex has an essential role in protein synthesis, but also in other biological processes including angiogenesis, apoptosis and inflammation. [PMID:21789020] AIMP3 is not only associated with the multi-tRNA synthetase complex via its specific interaction with methionyl-tRNA synthetase, but also works as a tumor suppressor by interacting with ATM, the upstream kinase of p53 [PMID:18343821].

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