- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, FC, IF, IHC
- 特异性:Human, Mouse, Rat; other species not tested.
产品详情
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产品名称
Cytokeratin 6A antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Cytokeratin 6A Rabbit Polyclonal antibody. Positive FC detected in HeLa cells. Positive IF detected in A431 cells, Hela cells. Positive IHC detected in human lung cancer tissue, human oesophagus tissue, human prostate cancer tissue, human skin tissue, human tonsil tissue. Positive WB detected in A431 cells, A375 cells, HeLa cells, MCF7 cells, rat skin tissue. Observed molecular weight by Western-blot: 56 kDa
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抗体应用
ELISA, WB, FC, IF, IHC
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应用推荐
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:20-1:200
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特异性
Human, Mouse, Rat; other species not tested.
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蛋白别名
CK 6A, CK 6D, CK6A, CK6C, CK6D, Cytokeratin 6A, Cytokeratin 6D, Hom s 5, K6A, K6C, K6D, keratin 6A, KRT conserve, KRT6, KRT6A, KRT6C, KRT6D, Type II keratin Kb6
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制备方法
This antibody was obtained by immunization of Cytokeratin 6A recombinant protein (Accession Number: NM_005554). Purification method: Antigen affinity purified.
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组分
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 6 is a type II keratin. It is used as marker for epidermal hyperproliferation and differentiation. Three keratin 6 isoforms were found, ketatin 6A,6B and 6C. They share more than 99% identical DNA sequence.