c-Myb antibody

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  • 抗体类型:多克隆
  • 抗体来源:
  • 抗体应用:ELISA, WB, IP
  • 特异性:Human,Mouse,Rat; other species not tested.

产品详情

  • 产品名称
    c-Myb antibody
  • 抗体类型
    多克隆
  • 抗体来源
  • 抗体亚型
    兔IgG
  • 抗体描述
    c-Myb Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells, Jurkat cells. Positive IP detected in HL-60 cells. Observed molecular weight by Western-blot: 72-80kd
  • 抗体应用
    ELISA, WB, IP
  • 应用推荐

    Recommended Dilution:

    WB: 1:200-1:1000

    IP: 1:200-1:1000

  • 特异性
    Human,Mouse,Rat; other species not tested.
  • 蛋白别名
    c myb_CDS, Cmyb, c-Myb, efg, MYB, Proto oncogene c Myb, Transcriptional activator Myb
  • 制备方法
    This antibody was obtained by immunization of c-Myb recombinant protein (Accession Number: NM_005375). Purification method: Antigen affinity purified.
  • 组分
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • 储存方法
    Store at -20℃. DO NOT ALIQUOT
  • 背景介绍
    The MYB protein is a transcription factor that plays a key role in regulating the proliferation/differentiation of progenitor cells in bone marrow, colonic crypts, and neurogenic niches [PMID:18574464]. It is involved in the regulation of epithelial-to-mesenchymal transition (EMT) and invasion in neuroblastoma, colon carcinoma, and embryonic kidney cells through the upregulation of the transcription repressor Slug [PMID:20622260]. It also a DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3', and plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

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