Anti-TNFRSF8 antibody

多克隆

兔

兔IgG

Rabbit Polyclonal to Mouse TNFRSF8

IHC-P

Mouse CD30 / TNFRSF8

Ki, Ki, CD30, Ki-1, D1S166E, Cd30, Ki-1, D1S166E, CD30, Cd30, D1S166E, D1S166E, Ki-1, Ki-1, RP23-306F22.1, TNFRSF8, Tnfrsf8

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse CD30 / TNFRSF8, and purified by antigen affinity chromatography.

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy