- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB, FC, IP
- 特异性:Human, Mouse, Rat
产品详情
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产品名称
Anti-N Cadherin Rabbit antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
N Cadherin Rabbit polyclonal antibody
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抗体应用
WB, FC, IP
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应用推荐
WB: 1/1000
FC: 1/100
IP: 1/20
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特异性
Human, Mouse, Rat
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蛋白别名
CDHN; NCAD; CD325; CDw325
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制备方法
Antigen: Recombinant protein of human N Cadherin
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组分
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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储存方法
Store at -20°C. Stable for 12 months from date of receipt.
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背景介绍
Swiss-Prot Acc.P19022.Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density .