Anti-CD131/CSF2RB/IL3RB/IL5RB antibody

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  • 抗体类型:单克隆
  • 抗体来源:小鼠
  • 抗体应用:FCM
  • 特异性:Human CD131 / CSF2RB / IL3RB / IL5RB

产品详情

  • 产品名称
    Anti-CD131/CSF2RB/IL3RB/IL5RB antibody
  • 抗体类型
    单克隆
  • 抗体来源
    小鼠
  • 抗体亚型
    小鼠IgG1
  • 抗体描述
    Mouse monoclonal to CD131/CSF2RB/IL3RB/IL5RB
  • 抗体应用
    FCM
  • 应用推荐
    FCM
  • 特异性
    Human CD131 / CSF2RB / IL3RB / IL5RB
  • 蛋白别名
    CD131, IL3RB, IL5RB, SMDP5, CDw131, Bc, Il3r, AIC2B, Il3rb, Il5rb, CDw131, Il3rb1, Csf2rb1, Csfgmrb, AI848964, AI848964, AIC2B, Bc, CD131, CDw131, CDw131, CSF2RB, Csf2rb1, Csfgmrb, GM-CSF/IL-3/IL-5 receptor common beta-chain, GM-CSF/IL-3/IL-5 receptor common beta-chain, Il3r, IL3RB, Il3rb, Il3rb1, Il5rb, IL5RB, MGC130522
  • 制备方法
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD131 / CSF2RB / IL3RB / IL5RB (rh CD131 / CSF2RB / IL3RB / IL5RB; NP_000386.1; Met1-Trp443) and conjugated with APC under optimum conditions, the unreacted APC was removed.
  • 组分
    Aqueous solution containing 0.5% BSA and 0.09% sodium azide
  • 储存方法
    This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
    Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
  • 背景介绍
    Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (IL3RB), is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this protein have been reported to be associated with protein alveolar proteinosis (PAP). CD131 belongs to the type I cytokine receptor family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Defects in CD131/CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5). SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
  • 参考文献
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