- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:WB, IF
- 特异性:Human, Mouse, Rat
产品详情
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产品名称
ADAMTS4 Polyclonal Antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
Polyclonal antibody to ADAMTS4
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抗体应用
WB, IF
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应用推荐
WB 1:500 - 1:2000
IF 1:50 - 1:200 -
特异性
Human, Mouse, Rat
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蛋白别名
ADAMTS4, ADAMTS-2, ADAMTS-4, ADMP-1, ADAM metallopeptidase with thrombospondin type 1 motif 4
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制备方法
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-315 of human ADAMTS4 (NP_005090.3).
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组分
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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储存方法
Store at -20℃. Avoid freeze / thaw cycles.
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背景介绍
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.