- 抗体类型:多克隆
- 抗体来源:兔
- 抗体应用:ELISA, WB, IHC, IF
- 特异性:Human, Mouse; other species not tested.
产品详情
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产品名称
acid phosphatase, prostate antibody
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抗体类型
多克隆
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抗体来源
兔
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抗体亚型
兔IgG
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抗体描述
acid phosphatase, prostate Rabbit Polyclonal antibody. Positive IF detected in PC-3 cells. Positive IHC detected in human prostate cancer tissue, human prostate hyperplasia tissue. Positive WB detected in PC-3 cells, COLO 320 cells, MCF7 cells, mouse lung tissue, mouse testis tissue. Observed molecular weight by Western-blot: 50-60 kDa
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抗体应用
ELISA, WB, IHC, IF
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应用推荐
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:20-1:200
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特异性
Human, Mouse; other species not tested.
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蛋白别名
acid phosphatase, prostate, ACP 3, ACP3, ACPP, PAP, Prostatic acid phosphatase
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制备方法
This antibody was obtained by immunization of acid phosphatase, prostate recombinant protein (Accession Number: NM_001134194). Purification method: Antigen affinity purified.
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组分
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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储存方法
Store at -20℃. DO NOT ALIQUOT
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背景介绍
ACPP is also named as PAP(prostatic acid phosphatase),5'-nucleotidase,thiamine monophosphatas and Belongs to the histidine acid phosphatase family.This enzyme is a homodimeric glycoprotein with a subunit molecular mass of 50 kDa and is an androgen-stimulated secretory product of the human prostate gland(PMID:8132635).It is also a non-specific phosphatase and has been implicated in the progression of prostate cancer, which inactivates LPA in human seminal plasma(PMID:15280042). This protein has three glycosylation sites(PMID:10639192;12525165).
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参考文献
- Bae H, Lim W, Bae SM, Bazer FW, Choi Y, Song G. Avian prostatic acid phosphatase: estrogen regulation in the oviduct and epithelial cell-derived ovarian carcinomas. Biology of reproduction. 91(1):3. 2014.
- Lim W, Bae H, Sohn JY, Jeong W, Kim SH, Song G. Dietary cholesterol affects expression of prostatic acid phosphatase in reproductive organs of male rats. Biochemical and biophysical research communications. 456(1):421-7. 2015.